Corticobasal degeneration (CBD) is a progressive neurological disorder. It is associated with atrophy of the cerebral cortex and the basal ganglia.
Corticobasal degeneration (CBD) generally occurs in patients age 45 to 70, with women affected more often than men. The combined loss of brain tissue in all these areas causes the symptoms. The initial symptoms often include stiff, shaky, slow and clumsy movements in either the arms or legs. Other early symptoms may include difficulty walking and balancing , short-term memory problems, difficulty controlling the muscles of the face and mouth.
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